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Symbol
Name
ID
Polg
polymerase (DNA directed), gamma
MGI:1196389
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Hypergonadotropic hypogonadism
Disease(s) Associated with POLG
autosomal dominant progressive external ophthalmoplegia 1

Mouse Phenotypes
abnormal crypts of Lieberkuhn morphology
decreased thymocyte number
seminiferous tubule degeneration
small testis
testicular atrophy
abnormal thymus involution
Availability Mouse Genotype
Polgtm1.1Lrsn/Polgtm1.1Lrsn
Polgtm1Prol/Polgtm1Prol

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory